Gurunathan Laxmikanthan, Nutter McClennen & Fish LLP Photo

Gurunathan Laxmikanthan

Technical Specialist / Boston


Gurunathan Laxmikanthan, Ph.D. is a Technology Specialist at Nutter. He works closely with Nutter’s Intellectual Property Department, providing assistance on patent prosecution, freedom-to-operate analysis, interferences proceedings, and infringement enforcement strategies in the fields of biochemistry, immunology, molecular and structural biology, and small molecules.

Guru’s extensive experience in biotech and life sciences encompasses many areas of research, including proteases, recombinases, organic and inorganic chemistry, structure-based drug design, electron microscopy, X-ray crystallography, and molecular modeling. He has developed novel structural methods using methylases to improve the contrast and signal-to-noise ratio for the feature of small macromolecular complexes in electron microscopy. Guru has successfully engineered a bi-directional Cre recombinase into a unidirectional co-factor dependent recombinase, identical to the classic paradigm system of Lambda integrase. In addition, he has designed a new method for assaying potential activators of proteases using hybrid proteins containing fragments from Fibroblast growth factors and sequences of preforms of kallikreins. He has also solved a high-resolution crystal structure of human kallikrein 1 during his graduate work.

Prior to joining Nutter, Guru was a technology specialist at a New England-based intellectual property law firm. Previously, he performed postdoctoral research in structural biology and molecular biology and was a research associate at Brown University, where he worked on the structural characterization of the bacteriophage lambda intasome complex using cryo-electron microscopy.

A member of the Sigma Xi Scientific Research Society, Guru received the Outstanding Pre-Doctoral Fellow Research Award from the American Heart Association. He has taught numerous laboratory and programming courses to undergraduates.

Guru earned his Ph.D. in biochemistry from Florida State University, his M.S. in chemistry from the Indian Institute of Technology, and his undergraduate degree from St. Joseph’s College in India.

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Florida State University, Ph.D.
Indian Institute of Technology, M.S.
St. Joseph's College

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